Publications by authors named "P Langley"

Article Synopsis
  • - The critique focuses on the failures in health technology assessment, emphasizing the lack of proper measurement standards in studies like the recent ICER report, which misapplies ordinal data from menopause quality of life questionnaires in cost-effectiveness models.
  • - It highlights the mathematical impossibility of directly converting multidimensional ordinal scores, leading to invalid claims regarding the cost-effectiveness of treatments like fezolinetant for menopause symptoms.
  • - The commentary advocates for using Rasch Measurement Theory to develop a more appropriate quality of life assessment tool for menopause, pushing for a shift in methodology that better supports informed decision-making in health technology evaluations.
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This empirical qualitative study explores the role of gaming simulations in catalyzing changes to organization-wide management's perspectives on a novel strategy for aircraft orders and retirements. A large US airline developed the new strategy to tackle the pervasive problem of profit cyclicality, driving poor average profit performance across the cycle. Based on the dynamic model used to develop the strategy with senior management, a gaming simulation workshop was designed and delivered in groups of 20 to over 200 organization-wide managers.

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This commentary proposes that Rasch Measurement Theory (RMT) is an innovative method for assessments of patient-centric therapy response in hemophilia A and B, as they are in other disease states or target patient populations. RMT is a necessary and sufficient approach to moving from ordinal observations to interval measurement, which has arithmetic properties. This applies across the board in hemophilia and other disease states for clinical value claims, patient centric or subjective value claims as well as those for anticipated drug utilization and other medical care resources.

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