Publications by authors named "P Lakshminarayanan"
Article Synopsis
- Abnormal uterine bleeding (AUB) is common in perimenopausal women, with heavy menstrual bleeding being the most frequent type, and it carries risks for endometrial cancer and hyperplasia.
- A study at Sree Balaji Medical College examined women aged 40-55 with heavy menstrual bleeding, assessing ultrasound findings and histopathology while excluding those on specific treatments.
- Results showed that a significant portion of participants had fibroids and endometrial hyperplasia; notably, an endometrial thickness over 8 mm correlated strongly with potential malignancies, highlighting the importance of ultrasound as a diagnostic tool.
Purpose: Early identification of patients who may be at high risk of significant weight loss (SWL) is important for timely clinical intervention in lung cancer radiotherapy (RT). A clinical decision support system (CDSS) for SWL prediction was implemented within the routine clinical workflow and assessed on a prospective cohort of patients.
Materials And Methods: CDSS incorporated a machine learning prediction model on the basis of radiomics and dosiomics image features and was connected to a web-based dashboard for streamlined patient enrollment, feature extraction, SWL prediction, and physicians' evaluation processes.
Purpose: Radiation-induced xerostomia is one of the most prevalent symptoms during and after head and neck cancer radiation therapy (RT). We aimed to discover the spatial radiation dose-based (voxel dose) importance pattern in the major salivary glands in relation to the recovery of xerostomia 18 months after RT, and to compare the recovery voxel dose importance pattern to the acute incidence (injury) pattern.
Methods And Materials: This study included all patients within our database with xerostomia outcomes after completion of curative intensity modulated RT.
Purpose: We investigate whether esophageal dose-length parameters (L) can robustly predict significant weight loss-≥5% weight loss during radiation therapy (RT) compared with the weight before RT-in patients with lung cancer treated with definitive intent.
Methods And Materials: Patients with lung cancer treated with conventionally fractionated RT between 2010 and 2018 were retrospectively identified. L and L, the length of full- and partial-circumferential esophagus receiving greater than a threshold dose in Gy, respectively, were created.
Objective: To explore relationships between dose to periprostatic anatomic structures and erectile dysfunction (ED) outcomes in an institutional cohort treated with prostate brachytherapy.
Methods: The Sexual Health Inventory for Men (SHIM) instrument was administered for stage cT1-T2 prostate cancer patients treated with Pd-103 brachytherapy over a 10-year interval. Dose volume histograms for regional organs at risk and periprostatic regions were calculated with and without expansions to account for contouring uncertainty.