Publications by authors named "P Lagrange"

Background: Pulmonary vein isolation (PVI) is successful in approximately 50% of patients with persistent atrial fibrillation (PsAF) at one year. Identifying pre-procedurally the patients who respond favorably to a PVI alone strategy could improve their management. The present study aims to assess the predictive value of clinical response to pre-ablation electrical cardioversion (ECV) to identify the responders to PVI.

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Article Synopsis
  • - The study evaluated the effectiveness of two PVC ablation techniques: multipolar mapping using a high-density catheter and point-by-point mapping with the ablation catheter, involving 698 patients across 10 hospitals from 2017 to 2021.
  • - Results revealed that the multipolar group had significantly better mapping efficiency (more activation points) and shorter procedure times, while both groups showed high acute success rates and midterm efficacy.
  • - Notably, patients undergoing left-sided PVC ablation had better midterm outcomes with the multipolar method, suggesting it may lead to more successful results in certain cases.
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Aims: Pulmonary vein isolation (PVI) guided by the Ablation Index (AI) has shown high acute and mid-term efficacy in the treatment of paroxysmal atrial fibrillation (AF). Previous data before the AI-era had suggested that wide-area circumferential ablation (WACA) was preferable to ostial ablation. However, with the use of AI, we hypothesize that ostial circumferential ablation is non-inferior to WACA and can improve outcomes in paroxysmal AF.

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Purpose: We aim to evaluate whether the use of a multielectrode mapping catheter could lead to higher efficacy of premature ventricular contraction (PVC) ablation.

Methods: Prospective, multicenter nonrandomized study of consecutive patients referred for PVC ablation from January 2018 to June 2021. Patients were separated into two groups: activation map performed with the PentaRay catheter (Study group) or with the ablation catheter (Control group).

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Background: Recurrences of atrial fibrillation (AF) after pulmonary vein isolation (PVI) are mainly due to pulmonary vein reconnection. However, a growing number of patients have AF recurrences despite durable PVI. The optimal ablative strategy for these patients is unknown.

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