Publications by authors named "P L Vernazza"
The SIMPL'HIV study investigated whether switching to dolutegravir (DTG) + emtricitabine (FTC) was noninferior to continuing combined antiretroviral therapy for maintaining HIV-1 suppression at 144 weeks. The study demonstrated that viral suppression, CD4 gains, adverse events, quality of life, and patient satisfaction were comparable between groups, confirming DTG + FTC's safety and efficacy for long-term management of HIV-1 infection.
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- * The likely cause of this meteorite influx is the breakup of a large asteroid in the main asteroid belt, which continues to produce over 20% of current meteorite falls.
- * Evidence suggests that the Massalia collisional family of asteroids in the inner belt is the most probable source of this event, aligning with the distribution of L chondrite-like materials found on Earth today.
Understanding the origin of bright shooting stars and their meteorite samples is among the most ancient of astronomy-related questions, which at larger scales has human consequences. As of today, only approximately 6% of meteorite falls have been firmly linked to their sources (Moon, Mars or asteroid (4) Vesta). Here we show that approximately 70% of meteorites originate from three recent break-ups of D > 30 km asteroids that occurred 5.
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- The SIMPL'HIV study aimed to compare the costs and effectiveness of dual maintenance therapy and simplified patient-centered monitoring (PCM) versus standard monitoring in HIV care over 48 weeks.
- It analyzed the financial implications of both treatment approaches, including costs for consultations, drug therapy, lab tests, and hospitalizations, and involved participants choosing more flexible monitoring options.
- Results indicated no significant difference in total costs between the PCM group and the standard monitoring group while also assessing secondary health outcomes such as renal function, lipids, glucose, weight, and patient satisfaction.
Aims Of The Study: We aimed to assess the extent of SARS-CoV-2 humoral immunity elicited by previous infections and/or vaccination among healthcare workers, and to identify reasons why healthcare workers decided against vaccination.
Methods: This nested cross-sectional study included volunteer healthcare workers from 14 healthcare institutions in German-speaking Switzerland. In January 2021, SARS-CoV-2 vaccines were available for healthcare workers.