Effectiveness of Two Types of Distraction Techniques in the Management of Pain and Anxiety during Dental Treatment in 6-9-year-old Children.

Aim: To determine the effectiveness of distraction with virtual reality (VR) distraction devices in comparison with mobile phone video games in the management of pain and anxiety during dental treatment in 6-9-year-old children.

Materials And Methods: It was a comparative observational study. A total of 33 children aged 6-9 years who reported to the department for their first dental visit were selected and the subjects were divided into three groups.

An comparison of calcium ions release and diffusion ability of calcium hydroxide-based intracanal medicament in combination with three different vehicles like propolis, chitosan, and propylene glycol.

Context: Calcium hydroxide, which is an intracanal medicament, is widely used in endodontics. Improvements can be made to its effectiveness, as calcium hydroxide is dependent on the vehicle.

Aim: The study aims to compare and evaluate the release and diffusion ability of calcium hydroxide when mixed with - propolis, chitosan, and propylene glycol.

Spatial transcriptomics stratifies psoriatic disease severity by emergent cellular ecosystems.

Whereas the cellular and molecular features of human inflammatory skin diseases are well characterized, their tissue context and systemic impact remain poorly understood. We thus profiled human psoriasis (PsO) as a prototypic immune-mediated condition with a high predilection for extracutaneous involvement. Spatial transcriptomics (ST) analyses of 25 healthy, active lesion, and clinically uninvolved skin biopsies and integration with public single-cell transcriptomics data revealed marked differences in immune microniches between healthy and inflamed skin.

Alterations in the cutaneous microbiome of patients with psoriasis and psoriatic arthritis reveal similarities between non-lesional and lesional skin.

Objectives: To investigate the cutaneous microbiome spanning the entire psoriatic disease spectrum, and to evaluate distinguishing features of psoriasis (PsO) and psoriatic arthritis (PsA).

Methods: Skin swabs were collected from upper and lower extremities of healthy individuals and patients with PsO and PsA. Psoriatic patients contributed both lesional (L) and contralateral non-lesional (NL) samples.

Standalone Ayurvedic treatment of high-risk COVID-19 patients with multiple co-morbidities: A case series.

We report a case-series of Ayurvedic treatment in seven COVID-19 positive patients with multiple co-morbidities, categorized as high-risk for poor outcome from SARS-CoV-2 infection. All of them recovered completely from their illness with resolution of symptoms following Ayurvedic treatment. The data was collected from patients treated during the early months of the COVID-19 pandemic (June 2020 to September 2020) at an out-patient Ayurvedic Clinic, Chennai, India.