Publications by authors named "P L Le Chevallier"

The challenge with synthetically modified biochars is that they are notoriously difficult to characterize, and a new characterization approach that circumvents the challenges posed by overlapping bands in IR spectra is needed. We report multinuclear NMR approaches successful in the easy identification and quantification of covalently-bound functional groups on the biochar surface using P{H} CPMAS NMR spectroscopy.

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Medical devices are susceptible to bacterial colonization and biofilm formation, which can result in severe infections, leading to prolonged hospital stays and increased burden on society. Antibacterial films have the potential to assist in preventing biofilm formation, thereby reducing administration of antibiotics and the emergence of antibiotic-resistant strains. In a previous study, a chitosan-based matrix crosslinked with tannic acid and loaded with gentamicin was reported.

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Acute myeloid leukemia (AML) with translocation t(8;16)(p11;p13) represents a rare entity that has been categorized as a disease-defining recurring cytogenetic abnormality with adverse risk in the 2022 European LeukemiaNet classification. This rating was mainly based on a retrospective analysis comprising patients from several large clinical trials, which, however, included only 21 patients treated with allogeneic stem cell transplantation (alloSCT). Therefore, the European Society for Blood and Marrow Transplantation performed a registry study on a larger cohort to evaluate the role of alloSCT in t(8;16) AML.

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Article Synopsis
  • Haploidentical hematopoietic cell transplantation (haplo-HCT) is increasingly used globally but remains uncommon in low- and middle-income countries, prompting a working group from the SFGM-TC to propose recommendations for implementation.
  • * The potential advantages of haplo-HCT include better accessibility to donors and lower costs; however, it should only be performed in experienced centers with a track record of related HLA-matched transplants.
  • * Regular evaluations are necessary to monitor the feasibility and outcomes of implementing haplo-HCT in these regions, particularly for patients lacking HLA-matched donors.*
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