Publications by authors named "P L Kuznetsov"
Article Synopsis
- The horse family (equids) has a rich fossil record showing significant evolutionary changes over the last 55 million years, with a wealth of ancient genomes sequenced to understand their domestication history.
- This study generated genome-wide data from 25 ancient equid specimens spanning 44,000 years in regions like Anatolia and Mongolia, revealing the presence of extinct species and new insights into their survival.
- The research also identified genetic differences among Asian wild asses and a common genetic signature in wild asses across continents, raising questions about the role of specific genetic changes in the extinction of certain equid species.
The fine structure of echiurid blood vessels in the proboscis is known in detail, but the circulatory system of the trunk is still understood mainly at the level of general anatomy. The trunk circulatory system was studied in Bonellia viridis females, and specialized podocytes were found to form the walls of the ring vessel and the anterior part of the ventral vessel. Podocytes were for the first time described in the echiurid circulatory system.
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- - Horses transformed human mobility, but the timeline of their domestication and integration as transport is debated, with new genetic data being used to clarify this history.
- - Analysis of 475 ancient horse genomes indicates that modern domestic horses were shaped by human intervention around 2200 BCE, after a domestication bottleneck began around 2700 BCE, leading to a significant expansion across Eurasia.
- - Evidence also suggests that there was early horse husbandry in central Asia at Botai around 3500 BCE, prior to the establishment of contemporary horse bloodlines, challenging the notion of large herds being linked to migrations around 3000 BCE.
Aim: To evaluate the efficacy and safety of riamilovir in the treatment of COVID-19 in adults.
Materials And Methods: The study included 180 patients with a laboratory-confirmed diagnosis of COVID-19 which fully meet the criteria for inclusion, non-inclusion and exclusion, signed a voluntary informed consent to participate in a clinical trial.
Results: The efficacy, good tolerability and safety of the drug riamilovir in the treatment of COVID-19 have been established.
The Yamnaya archaeological complex appeared around 3300BCE across the steppes north of the Black and Caspian Seas, and by 3000BCE reached its maximal extent from Hungary in the west to Kazakhstan in the east. To localize the ancestral and geographical origins of the Yamnaya among the diverse Eneolithic people that preceded them, we studied ancient DNA data from 428 individuals of which 299 are reported for the first time, demonstrating three previously unknown Eneolithic genetic clines. First, a "Caucasus-Lower Volga" (CLV) Cline suffused with Caucasus hunter-gatherer (CHG) ancestry extended between a Caucasus Neolithic southern end in Neolithic Armenia, and a steppe northern end in Berezhnovka in the Lower Volga.
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