Publications by authors named "P L Goller"

Background: Intracerebral schwannomas are rare tumors resembling their peripheral nerve sheath counterparts but localized in the CNS. They are not classified as a separate tumor type in the 2021 WHO classification. This study aimed to compile and characterize these rare neoplasms morphologically and molecularly.

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  • - The study details rare cases of skin tumors in Brazilian rainbow boas, identifying conditions similar to hemangioma and hemangioendothelioma, and examining possible links to boid inclusion body disease (BIBD).
  • - Thirteen snakes exhibited the skin lesions, with a mix of introduced animals and those bred in-house; lesions emerged over eight years, but no new cases were recorded in the last five years.
  • - Diagnostic tests confirmed BIBD in five snakes, alongside the presence of reptarenavirus in the tumors, suggesting a potential connection between the virus and the observed neoplastic conditions, warranting further research.
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Introduction: Prior exposure to others' facial expressions of pain can lead to a facilitation of pain responses, including its corresponding response channel, namely facial responses to pain. It has been questioned, however, whether this vicarious pain facilitation occurs only when observing others' pain or whether the observation of other negative expressions can trigger similar facilitation of facial responses to pain. The study aimed to test this, by comparing the impact of viewing others' facial expressions of pain versus another negative expression (sadness) and two control expressions (neutral, happiness) on facial responses to pain.

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  • This study aimed to evaluate targeted next-generation sequencing (NGS) as a method for diagnosing drug-resistant tuberculosis by reviewing existing data on its effectiveness and prevalence in detecting mutations across different gene targets.
  • The researchers conducted a systematic review and meta-analysis of various sources for publications related to targeted NGS from 2005 to 2022, focusing on studies that utilized the technique for drug resistance prediction in tuberculosis.
  • They assessed the diagnostic accuracy of targeted NGS by analyzing sensitivity and specificity compared to traditional drug susceptibility testing methods, using a Bayesian model for comprehensive results.
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Neural-tumor interactions drive glioma growth as evidenced in preclinical models, but clinical validation is limited. We present an epigenetically defined neural signature of glioblastoma that independently predicts patients' survival. We use reference signatures of neural cells to deconvolve tumor DNA and classify samples into low- or high-neural tumors.

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