Inappropriate secretion of antidiuretic hormone in postoperative scoliosis patients: the role of fluid management.

Study Design: The present study examined the hypothesis that hypotonic saline therapy before surgery was a major factor in the development of the syndrome of inappropriate antidiuretic hormone secretion.

Objectives: The influence of fluid therapy and its relationship to the syndrome of inappropriate antidiuretic hormone secretion was studied by measuring patient electrolyte and osmolar responses at given times after surgery.

Summary Of Background Data: Mild renal dysfunction and increased plasma antidiuretic hormone occurs after surgery.

Clinical use of the insulin infusion pump in 100 patients with type I diabetes.

We investigated the efficacy of insulin-pump therapy in insulin-dependent diabetics, aged 18 to 69 years, by comparing the metabolic control achieved in 100 patients using this technique with that previously obtained by conventional insulin therapy. Patients were followed during pump therapy for as long as 15 months. Fasting and nonfasting blood glucose levels (mean +/- S.