Acute glycemic changes in brain and subcutaneous tissue measured by continuous glucose monitoring system in hereditary hypertriglyceridemic rat.

Parallel glucose measurements in blood and other different tissues give us knowledge about dynamics of glycemia changes, which depend on vascularization, distribution space and local utilization by tissues. Such information is important for the understanding of glucose homeostasis and regulation. The aim of our study was to determine the time-lag between blood, brain, and adipose tissue during rapid glucose changes in a male hHTG rat (n=15).

[Surgical Treatment for Idiopathic Epiretinal Membrane].

Aim: To assess effectiveness of surgical treatment for idiopathic epiretinal membrane.

Material And Methods: Retrospective study included on 44 eyes out of 46 patients operated for idiopathic ERM in OFTAL Zvolen with a 20G PPV (32 patients) and posterior vitreous membrane ablation and 23G PPV (14 patients) from August 2008 to December 2014. After the extraction of epiretinal membrane, a peeling of ILM has been implemented following its Blue Membrane identification.

[New possibilities screening of refractive errors among children].

Purpose: To establish early detection of refractive errors among children in Slovakia. Different screening methods have been evaluated and compared in this work.

Materials And Methods: we have been working on a prospective study.

The relationship between glycemia, insulin and oxidative stress in hereditary hypertriglyceridemic rat.

The aim of this study was to determine the effects of insulin infusion on oxidative stress induced by acute changes in glycemia in non-stressed hereditary hypertriglyceridemic rats (hHTG) and Wistar (control) rats. Rats were treated with glucose and either insulin or normal saline infusion for 3 hours followed by 90 min of hyperglycemic (12 mmol/l) and 90 min of euglycemic (6 mmol/l) clamp. Levels of total glutathione (GSH), oxidized glutathione (GSSG) and total antioxidant capacity (AOC) were determined to assess oxidative stress.

[Short-term and long-term effect of metformin in type 1 diabetics].

Unlabelled: The objective of the investigation was to evaluate the effect of metformin added to the usual insulin treatment on insulin resistance, on the dose of substituted insulin and on the compensation of type 1 diabetes.

Method: The first part of the study lasted 3 months, it was an open prospective study. The group was formed by 22 type 1 diabetics, average age 38.