Publications by authors named "P Kyriakos"

Objective: Recently, psychological, and behavioral interventions such as cognitive functional therapy (CFT) has gained significant attention in musculoskeletal rehabilitation. We aimed to compare interventions with a CFT component in adults (>18 years old) suffering from chronic neck pain (CNP) or chronic whiplash associated disorders (>3 months) with another intervention or no intervention, in pain, disability, kinesiophobia, or any other reported outcome measure.

Results: One case-study and three randomized controlled trials met the eligibility criteria.

View Article and Find Full Text PDF

Introduction: Slipped capital femoral epiphysis (SCFE) is a rather uncommon fracture, occurring usually in adolescence, during a period of rapid growth. Various pathogenetic risk factors contributing to its development have been identified. We present the case of a 10-month-old male infant who developed SCFE in his left hip following an epileptic seizure.

View Article and Find Full Text PDF

Adriamycin (ADM) was chemically conjugated to a murine monoclonal antibody, A0011, which recognizes the c-erbB-2 product, via a disulfide bond using N-succinimidyl-3-(2-pyridyldithio) propionate (SPDP) and 2-iminothiolane (2-IT). The molar ratio of ADM to the monoclonal antibody ranged from 15:1 to 25:1 and enzyme-linked immunosorbent assay (ELISA) showed that the binding activity of the conjugate was almost retained. We compared the efficacy of A0011 alone, ADM alone, the A0011-ADM conjugate, against the human breast cancer cell lines SK-BR-3, MDA-MB-361, MCF-7, and BT-20.

View Article and Find Full Text PDF