Publications by authors named "P Kumaravel"

Packaged coconut water offers various options, from pure to those with added sugars and other additives. While the purity of coconut water is esteemed for its health benefits, its popularity also exposes it to potential adulteration and misrepresentation. To address this concern, our study combines Fourier transform infrared spectroscopy (FTIR) and machine learning techniques to detect potential adulterants in coconut water through classification models.

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A set of nine derivatives, including five brominated compounds, was synthesized and the structures of these novel compounds were confirmed using H and C NMR as well as ESI MS spectra. These compounds were tested on four different cancer cell lines, chronic myelogenous leukemia (K562), prostate cancer (PC3), colon cancer (SW620), human kidney cancer (Caki 1), and on healthy human keratocytes (HaCaT). MTT results reveal that two newly developed derivatives ( and ) exhibit selective action towards K562 cells and no toxic effect in HaCat cells.

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Article Synopsis
  • - The integration of biology and computational science has transformed our understanding of biological systems and paved the way for innovative solutions to global issues like disease and environmental challenges.
  • - Genetic engineering and biomolecular simulation are key components of this evolution, offering insights into molecular processes and enabling the development of advanced therapies for genetic disorders and new pharmaceuticals.
  • - The ongoing advancements in computational biology are expected to significantly impact fields like cancer treatment and environmental restoration, showcasing its potential to revolutionize our understanding and enhancement of biological systems.
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The novel coronavirus 2019 is spreading around the world and causing serious concern. However, there is limited information about novel coronavirus that hinders the design of effective drug. Bioactive compounds are rich source of chemo preventive ingredients.

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