Publications by authors named "P Kumaran"
Purpose: To analyze the incidence of spin in the abstracts of systematic reviews and meta-analyses investigating anterolateral ligament augmentation or lateral extra-articular tenodesis as treatment for anterior cruciate ligament injuries.
Method: Studies were identified using the Preferred Reporting Items for Systematic Reviews and Meta Analysis guidelines searching PubMed, Web of Science, and Scopus in November 2023. The abstracts were graded for the incidence of the 15 most common types of spin, and full texts were reviewed for AMSTAR 2 classification.
Background: To present rates of reporting bias in systematic reviews and meta-analyses investigating meniscal root repair.
Methods: In this systematic review, PubMed, Scopus and Web of Science databases were queried for studies that investigated meniscal root tears treated with root repair. Included studies were systematic reviews and/or meta-analyses published in peer-reviewed journals in the English language with available full-texts.
Previous reports have described failures of modular fluted tapered femoral stems secondary to fatigue failure at the modular junction. However, the present study is the first reported case of modular fluted tapered femoral component failure involving atraumatic fracture of the proximal body following revision total hip arthroplasty. The failure occurred in a 52-year-old female with a history of postmenopausal osteoporosis on bisphosphonates who sustained an atraumatic fracture of the proximal body of a modular revision femoral stem.
View Article and Find Full Text PDFEfficacy and tolerability of a 4-month ofloxacin-containing regimen compared to a 6-month regimen in the treatment of patients with superficial lymph node tuberculosis: a randomized trial.
BMC Infect Dis
July 2024
Article Synopsis
- Tuberculosis lymphadenitis is a common form of extra-pulmonary TB, traditionally requiring six months of treatment, but this study explored a potential four-month regimen using ofloxacin.
- The trial involved adult TB patients randomly assigned to either a four-month ofloxacin-based treatment or a traditional six-month regimen, with outcomes assessed based on TB recurrence and treatment success.
- Results showed the four-month regimen was as effective and safe as the six-month control, with similar rates of favorable response and manageable side effects, making it a promising alternative.
Article Synopsis
- Metabolic syndrome, affecting 25% to 40% of adults in Malaysia, includes obesity, high blood pressure, dyslipidaemia, and glucose intolerance, and is linked to cardiovascular disease.
- A systematic review analyzed 8 randomized controlled trials to evaluate the effectiveness of Nigella Sativa on metabolic syndrome parameters, focusing on studies published between 2011 and 2021.
- Results indicated that Nigella Sativa significantly improved lipid profiles and glycaemic indices, but showed mixed effects on blood pressure and body measurements, making it suitable as an adjunct therapy for metabolic syndrome.