Publications by authors named "P Kruszewski"

Background/objectives: Eosinophilic esophagitis (EoE) is an inflammatory disease of unclear etiology. The aim of this study was to use untargeted plasma metabolomics to identify metabolic pathway alterations associated with EoE to better understand the pathophysiology.

Methods: This prospective, case-control study included 72 children, aged 1-17 years, undergoing clinically indicated upper endoscopy (14 diagnosed with EoE and 58 controls).

View Article and Find Full Text PDF

Objectives: To compare presenting symptoms, comorbidities, disease, and treatment characteristics of a black pediatric eosinophilic esophagitis (EoE) group to a non-black pediatric EoE group.

Methods: A retrospective chart review consisting of pediatric patients diagnosed with EoE between the years of 2010 and 2018 at a single urban pediatric hospital system comprising 143 black pediatric patients compared with 142 non-black pediatric patients with similar distribution of age and sex.

Results: Both groups were majority male, and the median age of diagnosis between the black and non-black group was 5.

View Article and Find Full Text PDF
Article Synopsis
  • Transmission electron microscopy (TEM) and energy dispersive spectroscopy (EDS) revealed some structural anomalies like oxygen contamination in the upper layers of the AlN, although the initial atomic layers display perfect alignment.
  • The study also finds that the AlN layer facilitates a two-dimensional electron gas (2DEG), characterized by high current transport and specific tunneling mechanisms, aligning well with theoretical expectations for AlN/GaN interfaces.
View Article and Find Full Text PDF

Background: Eosinophilic esophagitis (EoE) is an increasingly recognized, chronic inflammatory disease. Recent reports suggest clinical differences between males and females.

Objective: To define the relevant molecular pathways that could be related to clinical phenotypes in children with EoE.

View Article and Find Full Text PDF