Publications by authors named "P Kristiansen"
Article Synopsis
- * Despite their importance, current RDTs suffer from limitations in clinical sensitivity and specificity, require significant funding for development, and struggle with implementation, especially in low-income countries due to insufficient investments and competing health priorities.
- * The recent World Health Assembly resolution highlights the need for enhanced diagnostic capabilities, but it lacks binding power, making it crucial to seek funding mechanisms like the Pandemic Fund to improve RDT development for better pandemic preparedness.
Bronchoscopy has a low risk of complications when diagnosing peripheral lung lesions suspected of malignancy, however the procedures do not always determine a diagnosis. Several modalities have been invented to improve the diagnostic yield, including radial endobronchial ultrasound and electromagnetic navigation, which are currently used by several departments in Denmark. Augmented fluoroscopy, CT-guided bronchoscopy and robotic bronchoscopy are not yet available in Denmark, but may improve the diagnostic work-up, as argued in this review.
View Article and Find Full Text PDFBackground: Incorrect glove use can cause cross-contamination and healthcare-associated infections. Previous research has identified reasons for this, such as lack of indication, improper changing, and poor hand hygiene post use. Limited research has investigated the reasons behind healthcare workers' glove usage.
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- Poly-proline II helices are special shapes found in proteins that help them interact with other molecules, making them flexible and often misinterpreted.
- Scientists discovered that a protein called YadA from a germ called Yersinia enterocolitica has a poly-proline II helix that helps it stick to a substance called heparin.
- The YadA protein needs specific parts to connect with heparin, and if host cells can’t produce heparin properly, they aren’t affected by YadA, which may help the germ cause disease in certain situations.
Reference materials are critical in assay development for calibrating and assessing their suitability. The devasting nature of the COVID-19 pandemic and subsequent proliferation of vaccine platforms and technologies has meant that there is even a greater need for standards for immunoassay development, which are critical to assess and compare vaccines' responses. Equally important are the standards needed to control the vaccine manufacturing processes.
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