Kikuchi-Fujimoto syndrome during pregnancy.

Necrotizing lymphadenitis of the Kikuchi-Fujimoto type developed in our patient during her first trimester of pregnancy, but she carried the infant to full term with no apparent adverse effect. Two subsequent pregnancies were not associated with reactivation of the disorder, nor with any recognizable adverse effect on the fetuses. A pregnancy should not be terminated because of Kikuchi-Fujimoto necrotizing lymphadenitis when it develops during the first trimester of pregnancy.

Effect of cimetidine on oral digoxin absorption.

Cimetidine is a commonly prescribed histamine 2-receptor antagonist used in the treatment of gastric acid-related disorders. Cimetidine can interact with a number of drugs, including theophylline, benzodiazepine sedative hypnotics, warfarin, and antiarrhythmics. Problems may occur in patients receiving drugs with a narrow therapeutic index when combined with cimetidine.

Safety and effectiveness of weight reduction using a very-low-calorie formulated food.

Careful medical and laboratory monitoring of 27 subjects during a 28-day use of a 330-calorie (Cal)/day liquid formula, with weight loss averaging 9.1 kg (range, 3.2 to 19.