Development of a sensitive high-throughput enzymatic assay capable of measuring sub-nanomolar inhibitors of SARS-CoV2 Mpro.

The SARS-CoV-2 main protease (Mpro) is essential for viral replication because it is responsible for the processing of most of the non-structural proteins encoded by the virus. Inhibition of Mpro prevents viral replication and therefore constitutes an attractive antiviral strategy. We set out to develop a high-throughput Mpro enzymatic activity assay using fluorescently labeled peptide substrates.

Emergency unmanned airborne spectrometric (HPGe) monitoring system.

After a nuclear or radiation event, emergency responders and radiation protection authorities need quick and credible information based on reliable accident and post-accident radiological data. However, risks to people in the vicinity of the source pose serious measurement challenges. Many problems could be solved by unmanned airborne monitoring systems, but the current ones are mostly based on non-spectrometric detectors carried by drones with low bearing, short flying range and flight time.

Electric Potential Profiles in a Model Single-Path Electrodialysis Unit.

Electrodialysis is an important electromembrane separation process anticipated to play a significant role in developing future technologies. It produces ion-depleted and ion-concentrated product streams, intrinsically suggesting the formation of spatial gradients of relevant quantities. These quantities affect local conditions in an electrodialysis unit.

Study of the Two-Line Element Accuracy by 1U CubeSat with a GPS Receiver.

There is a common practice to calculate orbital trajectories of space objects like satellites and space debris using Two-Line Element Sets (TLEs). However, TLEs provide rather coarse parameters for fine orbit computation and their precision varies with age of their issue and position of the satellite. The paper evaluates such induced position determination error using the comparison of a position calculated from TLE data for a small CubeSat class satellite and a position obtained from the on-board custom GPS receiver that is a part of such satellite payload.