Serum histidine-rich glycoprotein during pregnancy and hormone treatment.

The concentration of serum histidine-rich glycoprotein (HRG) was determined by radial immunodiffusion during weeks 27-42 of pregnancy in 110 pregnant women. HRG was also measured in serum from 11 lactating women 6 weeks post partum, from 11 women taking oral contraceptives, and from four women having progestin-releasing subcutaneous capsules used for contraception. The concentration of serum HRG decreased during the last trimester of pregnancy reaching a nadir at the 36-37th week (HRG 49 +/- 14 g/l, mean +/- SD).

The binding of porphyrins by ligandin.

Spectrophotometric and equilibrium-dialysis measurements show that ligandin (glutathione S-transferase B, EC 2.5.1.