Publications by authors named "P Kornprat"
BACKGROUND Superior mesenteric artery syndrome, also known as Wilkie's syndrome, is a rare etiology of obstruction of the lower duodenum between the superior mesenteric artery and aorta. It often presents with unspecific abdominal pain and laboratory findings, resulting in difficult diagnosis and treatment. CASE REPORT A 21-year-old male patient was admitted to our clinic with a 13-month history of coughing, ill feeling, night sweats, vomiting, unintentional weight loss, and epigastric pain.
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- Some studies found that specific gene markers (KRAS or BRAF) combined with other health factors can lead to bad results for people with liver cancer, making surgery not very helpful.
- The research looked at data from over 1,600 patients to see how long they lived after surgery and found many didn’t survive long, especially those with risky KRAS mutations.
- The findings suggest that in some cases, surgery might not be the best option for these patients, similar to those who only got treatment without surgery.
Article Synopsis
- Understanding different types of arterial blood supply is important for surgeries related to the liver, pancreas, and bile ducts (HPB) as well as general surgery.
- The article discusses an 84-year-old man who had a total pancreatectomy due to a tumor and had unique arterial variations, including a replacing right hepatic artery and a middle colic artery connected to the splenic artery.
- This case highlights a previously unreported combination of arterial configurations, specifically a type III supply according to Michel's classification and a middle colic artery variation.
Background: To date, only two studies have compared the outcomes of patients with liver-limited BRAF V600E-mutated colorectal liver metastases (CRLMs) managed with resection versus systemic therapy alone, and these have reported contradictory findings.
Methods: In this observational, international, multicentre study, patients with liver-limited BRAF V600E-mutated CRLMs treated with resection or systemic therapy alone were identified from institutional databases. Patterns of recurrence/progression and overall survival were compared using multivariable analyses of the entire cohort and a propensity score-matched cohort.