Two oral contraceptives, efficacy, serum proteins, and lipid metabolism. A comparative multicentre study on a triphasic and a fixed dose combination.

A triphasic, combined oral contraceptive containing 30 - 40 - 30 micrograms ethinyloestradiol (EE), and 50 - 75 - 125 micrograms levonorgestrel was compared with a fixed dose combination containing 30 micrograms EE and 150 micrograms desogestrel in a randomized multicentre trial in 193/199 women and 1 063/1 073 cycles, respectively. The duration of the trial was six months. Eleven centres in Denmark, Sweden, and Norway participated.

Oral contraceptives according to the normophasic principle.

A trial of a normophasic-principle oral contraceptive ethinylestradiol (Ovanon) is reported. In 130 women observed for a total of 1354 cycles, there were no pregnancies; good cycle control was attained; side-effects were rare, and there was a very high degree of acceptability.