Homozygosity of a Founder Variant c.1508dupC in Causes Congenital Myasthenia With Variable Severity.

Background And Objectives: Description of 15 patients with the same variant in causing congenital myasthenic syndrome (CMS).

Methods: Nine adult and 6 pediatric patients were studied with molecular genetic and clinical investigations.

Results: All patients were identified with the c.

Risk of childhood neoplasms related to neonatal phototherapy- a systematic review and meta-analysis.

Context: Observational studies have shown conflicting results as to whether exposure to neonatal phototherapy is associated with increased rates of childhood cancer.

Objective: To describe the rates of childhood neoplasms and cancer after neonatal phototherapy.

Data Sources: The CENTRAL, PubMed, Scopus, and Web of Science databases.

High-flow nasal cannula use in pediatric patients for other indications than acute bronchiolitis-a scoping review of randomized controlled trials.

The objective of the study is to summarize current literature on high-flow nasal cannula (HFNC) use for different indications in pediatric patient excluding acute bronchiolitis and neonatal care. The study design is a systematic scoping review. Pubmed, Scopus, and Web of Science databases were searched in February, 2023.

Pacifier use and breastfeeding in term and preterm newborns-a systematic review and meta-analysis.

The purpose of this study is to assess whether pacifier use is associated with breastfeeding success in term and preterm newborns and whether it influences hospitalization time in preterm newborns. Four databases were searched for randomized controlled trials (RCTs), and a systematic review and meta-analysis were conducted. The risk of bias and evidence quality, according to the GRADE methodology, were analyzed.

Ursodeoxycholic acid as adjuvant treatment to phototherapy for neonatal hyperbilirubinemia: a systematic review and meta-analysis.

Background: Neonatal hyperbilirubinemia is observed in most newborns, and 5-15% of neonates require phototherapy. Phototherapy is effective but often prolongs hospitalization and has both short-term and potential long-term harms. The aim of this systematic review and meta-analysis was to evaluate the role of ursodeoxycholic acid (UDCA) combined with phototherapy in neonatal hyperbilirubinemia.