Publications by authors named "P Kieslinger"
Article Synopsis
- - The study aimed to compare three rapid molecular tests for detecting influenza A/B RNA in patients with flu-like symptoms who needed hospitalization at Graz University Hospital.
- - Out of 312 samples, the tests from Alere, Roche, and Cepheid showed varying sensitivities (90.5%, 96.0%, and 97.0%) and specificities (99.4%, 97.6%, and 98.2%), with Roche also having a significant number of invalid results.
- - Although the Cepheid test took the longest to provide results (32 minutes), it performed the best overall in accurately detecting influenza virus RNA compared to the other tests evaluated.
Context: Contact with pollen is the major reason for the development of allergic symptoms on the ocular surface leading to a significant increase of allergic diseases worldwide. Environmental changes such as increased ultraviolet (UV) radiation and air pollution are discussed as contributory causes for this increase.
Objective: We investigated the effect of UV light on the histamine content of pollen and examined if an irradiation of pollen affects the viability and proliferation of conjunctival cells.
Using the menstrual cycle as a model, this study focused on longitudinal changes and associations within a physiological network known to play a role in female fertility, including, as biologically active nodes, NF-κB, leptin and adiponectin, β-carotene, adipose tissue, and progesterone. In 28 women, leptin, adiponectin, β-carotene, and progesterone concentrations, NF-κB p65 and p50 activation in peripheral blood mononuclear cells (known to possess estrogen, progesterone and leptin receptors), total body fat (TBF) and subcutaneous adipose tissue (SAT) mass were determined at early (T1) and late follicular (T2) and mid (T3) and late (T4) luteal phase. Leptin and adiponectin concentrations were higher, while NF-κB p65 activation was lower at T3 compared with T1.
View Article and Find Full Text PDFClotting abnormalities are discussed both in the context with thyroid dysfunctions and obesity caused by a high fat diet. This study aimed to investigate the impact of hypo-, or hyperthyroidism on the endogenous thrombin potential (ETP), a master indicator of clotting activation, on Sprague Dawley rats fed a normal or high fat diet. Female Sprague Dawley rats (n = 66) were grouped into normal diet (ND; n = 30) and high-fat diet (HFD; n = 36) groups and subdivided into controls, hypothyroid and hyperthyroid groups, induced through propylthiouracil or triiodothyronine (T3) treatment, respectively.
View Article and Find Full Text PDFArticle Synopsis
- Metabolic dysfunctions may significantly affect thyroid health, influencing conditions like hypothyroidism and hyperthyroidism.
- The study examined how normal and high-fat diets impacted thyroid dysfunctions in female Sprague Dawley rats, focusing on key metabolic parameters over 12 weeks.
- Results indicated that hyperthyroid rats had higher oxidized LDL levels, suggesting a greater risk for atherosclerosis, while hypothyroid rats showed lower oxidized LDL levels, particularly on a high-fat diet.