EFFECT OF SOME IMMUNOMODULATORY DRUGS ON EMBRYONIC DEVELOPMENT OF DANIO RERIO FISH.

At the current stage of healthcare development, the inclusion of immunomodulators in the complex pharmacotherapy of various immunoinflammatory and viral diseases is widely discussed, but due to the lack of sufficient research and a broad evidence base, not all drugs with similar properties are used in medicine. According to the information obtained from the instructions for the use of immunomodulators, it was obtained that the main contraindications to their use include the prescription of children, pregnant women, and women during breastfeeding. In this study, we evaluated the effects of immunomodulatory drugs: aminodihydrophthalazindione sodium and meglumine acridonacetate, on the early developmental stages of Danio rerio (Zebrafish) embryos.

[A new method for isolating and purifying estrogen-binding globulin from retroplacental serum].

A new method of obtaining of purified sex-hormone binding globulin SHBG is described. This method provides good reproducibility and large-scaling. The physico-chemical and immunochemical properties of the preparation obtained was identical to the preparations obtained by other authors.

[Filling out medical certificates (u. f. 086/u)].

The analysis of 1100 health certificates (Form 086/y) received by the selection committee of the Institute of Automated Systems and Radioelectronics showed that only 7.76% of them met the requirements. The rest of health certificates had the following faults: incompetence when determining physical fitness, insufficient data, diagnostic errors, inadequate drawing up of medical documents.