Publications by authors named "P Khaki"

Campylobacter infections are a prevalent cause of diarrheal disease in humans and are the most significant zoonotic pathogens worldwide. Human campylobacteriosis is generally via ingestion of contaminated poultry products. However, based on recent studies chicken egg yolk antibody (IgY) powder has great potential to reduce the cecum load of Campylobacter jejuni (C.

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Article Synopsis
  • The study focuses on cloning and sequencing a gene related to a protein that is preserved across different pathogenic serovars during infections.
  • 23 pathogenic and 2 non-pathogenic serovars were analyzed, sourced from a microbiology lab in Iran, with three serovars also used in a trivalent vaccine.
  • The results showed that the gene was present in all pathogenic serovars but absent in non-pathogenic ones, highlighting its potential for creating an effective recombinant vaccine due to its high conservation (95.5% to 100% similarity).
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Leptospirosis is a worldwide zoonotic disease caused by pathogenic spp, often occurring in tropical and subtropical regions. Focusing on development of rapid diagnostic methods to facilitate early diagnosis and a universal vaccine are the main critical issues to overcome the burden of leptospirosis. Here, we have studied the immunogenic potential of prepared recombinant Loa22 protein (rLoa22) of local pathogenic species in mice and its ability to induce humoral and cellular immunity, being further evaluated by analyzing the immunoglobulin G (IgG) subclasses and cytokines produced through immunization.

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Background And Objectives: Leptospirosis is an infectious zoonotic disease that can result in severe complications. It is widespread, especially in hot and humid climates such as the northern region of Iran. The immune responses to leptospirosis are multifaceted.

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Background And Objectives: Leptospirosis is a zoonotic disease caused by pathogenic serovars. The genus cannot differentiated by conventional techniques. However, identity determination of pathogenic serovar is precious of public health problems and epidemiological studies.

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