Publications by authors named "P Khairallah"
Rationale & Objective: Atrial fibrillation (AF) is common in patients with kidney failure on hemodialysis (HD), but few patients receive oral anticoagulant (OAC) treatment. Availability of direct-target OACs starting in 2010 may have induced greater OAC initiation, but this has not been systematically studied.
Study Design: Retrospective cohort study.
Article Synopsis
- - The study analyzed trends in waitlisting, re-transplantation, and mortality rates among U.S. kidney transplant patients whose first graft failed, using data from the United States Renal Data System between 1990 and 2019.
- - Results showed that while the number of patients starting dialysis after graft failure increased, the rate of waitlisting for second transplants initially rose but later fell, and re-transplantation rates consistently decreased across the years.
- - Notably, there were disparities in outcomes based on gender and race, with women and minority groups (African-American and Hispanic patients) experiencing lower rates of waitlisting and re-transplantation compared to men and White patients.
Rationale & Objective: Atrial fibrillation is the most common arrhythmia and is increasing in prevalence. The prevalence of atrial fibrillation is high among patients receiving dialysis, affecting ∼21.3% of the patients receiving hemodialysis and 15.
View Article and Find Full Text PDFPurpose Of Review: To summarizes the literature on cellular senescence and frailty in solid-organ transplantation and highlight the emerging role of senotherapeutics as a treatment for cellular senescence.
Recent Findings: Solid-organ transplant patients are aging. Many factors contribute to aging acceleration in this population, including cellular senescence.