Publications by authors named "P Karunakar"
Aim: Undernurition stands as a significant contributor to childhood mortality, particularly in developing nations such as India. At the grass root level, anthropometric monitoring indicators such as stunting, underweight and wasting take place within Anganwadi centres (village courtyard). The scrutiny of growth records, utilising these markers, not only quantifies the burden but also informs corrective measures.
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- A study has been conducted to identify new drug targets to combat a highly lethal pathogen causing tuberculosis, focusing on essential proteins like biotin synthase and alpha-(1->6)-mannopyranosyltransferase A involved in specific biosynthesis pathways.
- Researchers used bioinformatics tools to model proteins without native structures and explored interactions with natural compounds derived from selected mushrooms.
- Out of 15 identified bioactive compounds, four were chosen for further analysis, with Benz[e]azulene showing promising binding affinity to a specific target, indicating the potential of mushroom extracts in developing new TB treatments.
Aim: To evaluate the efficacy of Neo-endo, Hyflex retreatment file systems, and H-files for removing gutta-percha from root canal treated tooth.
Materials And Methods: Thirty extracted single-rooted human teeth with a single canal were opted. The shaping of the root canals was done with pro-taper universal files and later obturated.
A rare case of congenital insensitivity to pain with anhidrosis.
Paediatr Int Child Health
August 2024
A 22-month-old girl of consanguineous parents was admitted with a high-grade fever. She was found to have insensitivity to painful stimuli and an absence of perspiration. She also displayed self-mutilating behaviour and was insensitive to cold/hot water on her body.
View Article and Find Full Text PDFObjective: Significant involvement of the cardiovascular system is known in multisystem inflammatory syndrome in children (MIS-C). This study aimed to examine the recovery of affected cardiovascular parameters over a medium-term follow-up.
Methods: A cohort of 69 children was studied prospectively.