Publications by authors named "P Karoly"

Objective: Epileptic seizures occurring in cyclical patterns is increasingly recognized as a significant opportunity to advance epilepsy management. Current methods for detecting seizure cycles rely on intrusive techniques or specialized biomarkers, thereby limiting their accessibility. This study evaluates a non-invasive seizure cycle detection method using seizure diaries and compares its accuracy with cycles identified from intracranial electroencephalography (iEEG) seizures and interictal epileptiform discharges (IEDs).

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Article Synopsis
  • - The study introduces "pro-ictal EEG scheduling," a new method for timing video-electroencephalography (vEEG) sessions to improve the detection of epileptic activity by aligning them with high-risk seizure periods.
  • - Analyzing data from over 5,000 vEEG sessions and related seizure diaries, the research found that monitoring during high-risk periods led to significantly higher rates of abnormal reports, confirmed seizures, and reported events compared to regular monitoring times.
  • - The findings, which highlight the effectiveness of this scheduling method, suggest that pro-ictal EEG scheduling can be a practical and low-risk strategy to enhance epilepsy diagnosis and management.
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Objective: Over recent years, there has been a growing interest in exploring the utility of seizure risk forecasting, particularly how it could improve quality of life for people living with epilepsy. This study reports on user experiences and perspectives of a seizure risk forecaster app, as well as the potential impact on mood and adjustment to epilepsy.

Methods: Active app users were asked to complete a survey (baseline and 3-month follow-up) to assess perspectives on the forecast feature as well as mood and adjustment.

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Objective: Epilepsy management employs self-reported seizure diaries, despite evidence of seizure underreporting. Wearable and implantable seizure detection devices are now becoming more widely available. There are no clear guidelines about what levels of accuracy are sufficient.

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