Publications by authors named "P K Tewarie"
Blood-level oxygenation-dependent (BOLD) functional magnetic resonance imaging (fMRI) is the most common modality to study functional connectivity in the human brain. Most research to date has focused on connectivity between pairs of brain regions. However, attention has recently turned towards connectivity involving more than two regions, that is, higher-order connectivity.
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- Zolpidem can trigger brief and impressive improvements in brain functions for some patients with severe brain injury, especially when paired with deep brain stimulation (DBS).
- This study focused on a patient whose motivation and arousal were improved through DBS treatment targeting a specific brain area, resulting in significant functional gains like communication and mobility.
- Findings showed that DBS reduces excessive brain connectivity, suggesting that less connectivity could enhance cognitive function post-injury, providing insights for future therapies.
Computational models are often used to assess how functional connectivity (FC) patterns emerge from neuronal population dynamics and anatomical brain connections. It remains unclear whether the commonly used group-averaged data can predict individual FC patterns. The Jansen and Rit neural mass model was employed, where masses were coupled using individual structural connectivity (SC).
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