Publications by authors named "P K Moore"
Purpose Of Review: Chronic low back pain (LBP) is a prevalent and debilitating condition affecting millions worldwide. Among emerging interventions, spinal cord stimulation (SCS) has gained attention as a potential alternative for managing chronic LBP, particularly when alternative approaches fail to provide adequate relief.
Recent Findings: This systematic review focuses on both residual pain levels and ability to perform daily tasks after treatment with SCS.
Objectives: Fatigue is commonly reported in patients with Crohn's disease (CD) and ulcerative colitis (UC), including patients with inactive disease. We explored the impact of fatigue on healthcare utilization (HCU) and work productivity and activity impairment (WPAI).
Methods: Data collected between 2017 and 2022 were analyzed from the CorEvitas IBD Registry.
Objectives: To compare effectiveness of tofacitinib versus tumor necrosis factor inhibitors (TNFi), and across tofacitinib lines of therapy, in patients with rheumatoid arthritis (RA), using US CorEvitas RA Registry data.
Methods: Analysis included patients with RA initiating tofacitinib or TNFi with a 12-month follow-up visit between November 2012-February 2021. Primary (Clinical Disease Activity Index-defined low disease activity [CDAI-LDA: CDAI ≤ 10]) and secondary (clinical/disease activity/patient-reported) effectiveness outcomes were assessed at month 12.
Molecular dynamics simulations are a powerful tool for probing and understanding the theoretical aspects of chemical systems and solutions. Our research introduces a novel method for determining the excess chemical potential of non-ideal solutions by leveraging the equivalence between the chemical potential of the vapor phase and liquid phase. Traditional approaches have relied on bulk simulations and the integration of pair distribution functions (()), which are computationally intensive to obtain accurate results.
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