Objective: To examine existing literature regarding health literacy levels and their association with multimorbidity and the potential underlying mechanisms behind the said association.
Design: Systematic review and meta-analysis.
Data Sources: The databases MEDLINE, EMBASE, CINAHL and Science Direct were searched for articles published between 1 January 2000 and 31 October 2023 using a systematic search strategy.
Background: The UK's National Health Service (NHS) is grappling with rising demand and limited dermatologists, leading to longer waiting times. This is particularly concerning for conditions like malignant melanoma, where early diagnosis is crucial. Teledermatology is being introduced to address these issues, but its impact on patients' monetary and time costs, especially in deprived areas, is under-researched.
View Article and Find Full Text PDFHomeotic transformation of tail to hindlimbs in anuran tadpoles is a manifestation of the reprogramming of positional information in the event of tail regeneration. Such discovery of homeosis is of particular interest considering its occurrence in a vertebrate under the influence of a morphogen which represents a self-organizing system in the context of developmental and regenerative studies. This article reviews homeotic transformation of tail to hindlimbs including pelvic girdles induced by retinoic acid (RA) /vitamin A palmitate during tail regeneration under the scope of self-organization and the role of blastema as an organizer.
View Article and Find Full Text PDFGrafting is a technique that involves attaching a rootstock to the aerial part of another genotype or species (scion), leading to improved crop performance and sustainable growth. The ability to tolerate abiotic stresses depends on cell membrane stability, a reduction in electrolyte leakage, and the species of scion and rootstock chosen. This external mechanism, grafting, serves as a beneficial tool in influencing crop performance by combining nutrient uptake and translocation to shoots, promoting sustainable plant growth, and enhancing the potential yield of both fruit and vegetable crops.
View Article and Find Full Text PDFThough mitochondria have their own genome and protein synthesis machineries, the majority of the mitochondrial proteins are actually encoded by the nuclear genome. Most of these mitochondrial proteins are imported into specific compartments of the mitochondria due to their mitochondrial target sequence (MTS). Unlike the nuclear target sequence, the MTS of most of the mitochondrial localized proteins remain poorly understood, mainly due to their variability, heterogeneity, unconventional modes of action, mitochondrial potential-dependent transport, and other complexities.
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