Background: Monitoring biologic drug therapy during pregnancy in women with immune-mediated inflammatory diseases (IMIDs) is crucial to ensure treatments align with evidence-based practices.
Research Design And Methods: A retrospective cohort study based on healthcare claims data from eight Italian regions was conducted, analyzing deliveries between 2009 and 2021. The study included women receiving biologic drugs within nine months before their last menstruation.
The synthesis and characterization of a novel bis-urea-based cage receptor for anions (3S,15S)-3,15,20,25-tetramethyl-1,4,6,12,14,17,20,25-octaazatricyclo[15.5.5.
View Article and Find Full Text PDFIntruding surface water can impact the physicochemical and microbiological quality of groundwater. Understanding these impacts is important because groundwater provides much of the world's potable water, and reduced quality is a potential public health risk. In this study, we monitored six shallow groundwater wells and three surface water bodies in the North Ostrobothnia region of Finland twice monthly for 12 months (October 2021-October 2022) via (i) on-site and off-site measurements of physicochemical water quality parameters, (ii) determination of stable water isotope compositions, and (iii) analysis of microbial communities (via amplicon sequencing of the V3-V4 16S rRNA gene sub-regions).
View Article and Find Full Text PDF