In vivo toxicological evaluation of 3-benzylideneindolin-2-one: antifungal activity against clinical isolates of dermatophytes.

Background: Dermatophytes, the primary causative agents of superficial cutaneous fungal infections in humans, present a significant therapeutic challenge owing to the increasing prevalence of recurrent infections and the emergence of antifungal resistance. To address this critical gap, this study was designed to investigate the antifungal potential of 3-benzylideneindolin-2-one against dermatophytes and assess its in vivo toxicological profile using brine shrimp and zebrafish embryo models.

Methods: The antifungal activity of 3-benzylideneindolin-2-one was evaluated against 30 clinical isolates of dermatophyte species, including Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum gypseum, Microsporum canis, and Epidermophyton floccosum, by determining the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) using the broth microdilution method.

Impact of compact TiO interface modification on the crystallinity of perovskite solar cells.

The effect of TiO interfacial morphology on perovskite crystallinity was investigated by modifying the micro and nanoscale surface roughness of compact TiO. While surface treatments of the compact TiO layer are recognized as effective strategies to enhance the photovoltaic performance of perovskite solar cells, the discussion regarding the crystallinity of perovskite atop TiO has been limited. In this study, we explored the impact of micro and nano scale interface morphology on perovskite crystal formation and its subsequent effects on device performance.

Catalytic reduction of 4-nitrophenol using CuO@NaTi(PO)⋅HO.

This article presents the synthesis, property characterization and catalytic application of CuO-supported disodium titanium phosphate, (CuO@NaTi(PO)⋅HO) for the reduction of industrial pollutant 4-nitrophenol (4-NP). A simple hydrothermal route was developed to synthesize CuO@NaTi(PO)⋅HO catalyst (CuO@NaTiP) from beach sand ilmenite. The prepared CuO@NaTiP was characterized using X-ray diffraction, scanning electron microscopy, energy dispersive X-ray analysis, X-ray photoelectron spectroscopy, and nitrogen adsorption-desorption isotherms.

Evaluation of learning environment among Nursing undergraduates in state universities, Sri Lanka.

Background: The learning environment is a vital part of the undergraduate curriculum which enable to delivery of quality education in the stipulated time. Therefore, this study aimed to evaluate the learning environment among BSc. Nursing undergraduates in Sri Lankan state universities.

Flue Gas Desulfurization (FGD) Wastewater Treatment Using Polybenzimidazole (PBI) Hollow Fiber (HF) Membranes.

Polybenzimidazole (PBI) hollow fiber membranes were used to treat flue gas desulfurization (FGD) wastewater (WW) from a coal fired power plant. Membranes were tested using both single salt solutions and real FGD WW. The PBI membranes showed >99% rejection for single salt solutions of NaCl, MgCl, CaSO, and CaCl at approximately 2000 PPM (parts per million).