Treatment of Open Bite Based on Skeletal Anchorage Using Extrusion Lever Arms and Class III Elastics.

A 26-year-old woman had a masticatory dysfunction, straight profile, retrognathic maxilla and mandible, and Angle's class I with a tendency to class III malocclusion on both sides, with bilateral posterior crossbites and a 4 mm anterior open bite. Orthognathic surgery and orthodontic camouflage with and without tooth extraction were considered as treatment options. The patient's preferred method of treatment was orthodontic camouflage without extraction.

Comparative In Vitro Biocompatibility Study of the Two Orthodontic Bonding Materials of Different Types.

In the present study, the in vitro biocompatibility and cell response to two commonly used orthodontic bonding materials of different types, one self-curing and one light-curing, were examined and compared in indirect and direct cell culture systems. The study was conducted on fibroblasts and macrophages as in vitro models to study the biocompatibility of dental materials. Differences were found between the light- and self-curing material in cytotoxicity and effects on fibroblasts' proliferation in indirect cell culture systems as well as in macrophages response in vitro in both direct and indirect cell culture systems.

Nitric oxide synthesis modulation - a possible diagnostic and therapeutic target in colorectal cancer.

Purpose: Considering the contradictory literature data about the role of nitric oxide (NO) in colon carcinogenesis, the purpose of this study was to examine the changes of L-arginine metabolites in colon cancer and surrounding tissue as possible molecular markers of tumor behavior after surgery and the possibility of NO synthesis modulation in new individualized therapeutic strategies.

Methods: The study encompassed 50 patients who underwent surgery for colorectal cancer (CRC). The three tissue specimens were taken by surgery (tumor, adjacent and healthy tissue) and the concentrations of NO2+NO3, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) were determined in the tissue specimens.

Index of orthodontic treatment need in children from the Niš region.

Background/aim: The Index of Orthodontic Treatment Need (IOTN) is a scoring system for malocclusion that con- sists of the two independent components: Denal Health Component (DHC) and Aesthetic-Component (AC). IOTNs are usually used in the countries with dental healthcare financed by the government through the national healthcare system or healthcare insurance. The aim of the study was to determine IOTN in primary school children from the town of Niš and to asses percent of children with any kind of orthodontic treatment.