Non-trivial dynamics in a model of glial membrane voltage driven by open potassium pores.

Despite the molecular evidence that a nearly linear steady-state current-voltage relationship in mammalian astrocytes reflects a total current resulting from more than one differentially regulated K conductance, detailed ordinary differential equation (ODE) models of membrane voltage V are still lacking. Various experimental results reporting altered rectification of the major Kir currents in glia, dominated by Kir4.1, have motivated us to develop a detailed model of V dynamics incorporating the weaker potassium K2P-TREK1 current in addition to Kir4.

Measurement-oriented deep-learning workflow for improved segmentation of myelin and axons in high-resolution images of human cerebral white matter.

Background: Standard segmentation of high-contrast electron micrographs (EM) identifies myelin accurately but does not translate easily into measurements of individual axons and their myelin, even in cross-sections of parallel fibers. We describe automated segmentation and measurement of each myelinated axon and its sheath in EMs of arbitrarily oriented human white matter from autopsies.

New Methods: Preliminary segmentation of myelin, axons and background by machine learning, using selected filters, precedes automated correction of systematic errors.

[Uretero-transappendix-cystoneostomy as a technique for the reconstruction of the lower part of the ureter].

Background: Any large missing part of the ureter may be replaced by transureteroureterostomy, psoas hitch, Boari flap, nephrectomy, renal autotransplanation or by the implementation of an intestinal graft.

Case Report: A patient with a defect of the lumbal-pelvic portion of the right ureter, after the managemenet of a penetrating and perforating gun shot wound was presented. The missing part of the ureter was seccessfully replaced with an appendix.

[War injuries of the rectum and perineum].

The treatment results of 35 wounded with rectal and perineal lesion, treated in the period from 1991 to 1993 were analyzed retrospectively. In military hospitals, 82% of wounded were primarily surgically managed. The majority (65.