Publications by authors named "P J Weidle"

Article Synopsis
  • - Since May 2022, mpox (monkeypox) has spread to 108 countries, predominantly affecting gay and bisexual men.
  • - Two studies conducted in mid-2022 revealed that 8% of men who have sex with men in San Francisco had orthopoxvirus antibodies, while approximately 5.6% of samples from across the U.S. tested positive for monkeypox.
  • - The findings suggest that there are likely very few undiagnosed mpox cases in areas with good sexual healthcare access and heightened awareness among patients and healthcare providers.
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Article Synopsis
  • HIV-related immunosuppression can raise the chances of hospitalization for mpox.
  • In Georgia, a study assessed how HIV status affects hospitalization rates among mpox patients.
  • Individuals with HIV who have a low CD4 count (<350 cells/mm3) or are not receiving HIV treatment are more likely to be hospitalized due to mpox.
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To examine the potential impact of contact tracing to identify contacts and prevent mpox transmission among gay, bisexual, and other men who have sex with men (MSM) as the outbreak expanded. We assessed contact tracing outcomes from 10 US jurisdictions before and after access to the mpox vaccine was expanded from postexposure prophylaxis for persons with known exposure to include persons at high risk for acquisition (May 17-June 30, 2022, and July 1-31, 2022, respectively). Overall, 1986 mpox cases were reported in MSM from included jurisdictions (240 before expanded vaccine access; 1746 after expanded vaccine access).

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Article Synopsis
  • - The study examined the prevalence of mpox virus in blood, throat, and rectal samples from people without visible rashes who were seeking the JYNNEOS vaccine.
  • - Findings suggest that testing individuals without skin lesions for mpox using throat, rectal, or blood samples may not be very effective.
  • - This raises questions about the practicality of risk-based screening for mpox in those who do not show typical symptoms.
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Background: A collaborative, data-to-care strategy to identify persons with HIV (PWH) newly out-of-care, combined with an active public health intervention, significantly increases the proportion of PWH re-engaged in HIV care. We assessed this strategy's impact on durable viral suppression (DVS).

Methods: A multisite, prospective randomized controlled trial for out-of-care individuals using a data-to-care strategy and comparing public health field services to locate, contact, and facilitate access to care versus the standard of care.

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