Publications by authors named "P J Vassilakos"
Performance of visual inspection, partial genotyping, and their combination for the triage of women living with HIV who are screen positive for human papillomavirus: Results from the AIMA-CC ANRS 12375 multicentric screening study.
Pierre Debeaudrap Firmin Nongodo Kabore Limsreng Setha Joseph Tegbe Brahima Doukoure Pierre Vassilakos
Int J Cancer
February 2025
Article Synopsis
- - The WHO recommends HPV testing for cervical cancer screening due to its high sensitivity, but further triage is needed to identify women with high-grade lesions (CIN2+) who need treatment.
- - The ANRS-12375 study evaluated various triage methods like visual inspection (VIA) and different genotyping options in Côte d'Ivoire, Burkina Faso, and Cambodia to detect CIN2+ lesions among women living with HIV.
- - Results showed that VIA and extended genotyping had high sensitivity (89%), with VIA also exhibiting the best specificity among the tests, making them effective options for identifying women who require treatment for CIN2+.
Objective: To assess the impact of thermal ablation (TA) for the treatment of cervical dysplasia on fertility and pregnancy outcomes among women screened for cervical cancer in Cameroon.
Design: Retrospective cohort study.
Setting: Dschang health district, Cameroon.
Article Synopsis
- The objective of the study was to find out if understanding cytology improves colposcopists' accuracy in diagnosing cervical intraepithelial neoplasia grade 2 and worse (≥ CIN2).
- Healthcare professionals evaluated colposcopy images from 80 patient cases in two surveys, one with cytology information and one without, to see how it affected their diagnostic decisions.
- Results showed that knowing cytology significantly increased sensitivity to 63.7% and specificity to 76.6%, indicating that better cytology information leads to more accurate diagnoses of ≥ CIN2 lesions.
Background: Screening participation at recommended intervals is a crucial component of cervical cancer prevention effectiveness. However, little is known regarding the rate of re-screening in a Sub-Saharan context. This study aimed to estimate the re-screening rate of women in a semi-rural after an initial HPV-based screening and identify factors that influence adherence.
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