Publications by authors named "P J Van Genderen"
Article Synopsis
- Travellers to rabies-endemic countries often lack adequate knowledge about the virus and risk prevention, with over 21% having poor understanding.
- A study involving Dutch travellers showed significant gaps in knowledge about transmission (like cats and bats) and post-exposure prophylaxis (PEP) requirements.
- To improve safety, there is a call for enhanced pre-travel education focusing on avoiding animal contact and understanding when to seek PEP after potential exposure.
Background: After rabies pre-exposure prophylaxis (PrEP) vaccination, scarcely available rabies immunoglobulins are not required for post-exposure prophylaxis (PEP). However, PrEP is not sufficiently accessible as it is cost-intensive and time-intensive. This study investigates whether rabies PrEP schedules can be shortened to one visit, removing some of these barriers.
View Article and Find Full Text PDFBy longitudinally following a large cohort of intercontinental travellers, this study highlights the importance of considering multiple risk factors to comprehend post-infectious irritable bowel syndrome (PI-IBS). Stomach cramps, antibiotic use and nausea during travel were amongst the variables that predicted PI-IBS development following an episode of traveller’s diarrhoea.
View Article and Find Full Text PDFBackground: Here we assessed a possible relationship between baseline TGF-β concentrations and acquisition of sterile immunity after Plasmodium falciparum sporozoite immunization.
Methods: TGF-β concentrations were determined in samples of 65 malaria-naive volunteers in 4 studies either prior to and after challenge infection, or prior to and after first immunizing infection under chemoprophylaxis with P. falciparum sporozoites.