Mapping of a congenital microcoria locus to 13q31-q32.

Congenital microcoria is an autosomal dominant disorder characterized by a pupil with a diameter <2 mm. It is thought to be due to a maldevelopment of the dilator pupillae muscle of the iris, and it is associated with juvenile-onset glaucoma. A total genome search for the location of the congenital microcoria gene was launched in a single large family.

Multivariate analysis versus vector analysis to assess surgically induced astigmatism.

Purpose: To present a multivariate probability computation method for assessing surgically induced astigmatism.

Setting: Department of Ophthalmology, Rennes University Hospital, Rennes School of Medicine, France.

Methods: The multivariate method was used to evaluate 100 patients who had cataract surgery by phacoemulsification.

Excimer laser photorefractive keratectomy to correct astigmatism.

Purpose: To evaluate the efficacy of excimer laser photorefractive keratectomy (PRK) to correct astigmatism.

Setting: Hôpital Morvan, Brest, France.

Methods: A 193 nm excimer laser was used to perform toric ablation with an expanding slit to flatten the cornea in the steeper meridian and/or to correct myopia with an iris diaphragm in 72 eyes (55 patients): 68 eyes for compound myopic astigmatism and 4 for astigmatism only.

[Multiple pilomatricoma. Apropos of a case].

Pilomatricoma is a benign, solitary tumor. The histopathologic findings of viable basaloid cells in the periphery, shadow cells in the central part and foci of calcification are characteristic of pilomatricoma. The microscopic aspect of multiple pilomatricomas was not different from solitary pilomatricomas.