Publications by authors named "P J Symons"

Objective: This study aimed to describe the placental changes occurring in women with preexisting diabetes mellitus and to determine if elastography can detect placental changes in vivo.

Data Sources: PubMed, Embase, Medline, and Cochrane were searched to identify English language studies published until July 2020.

Study Eligibility Criteria: 1) For key question 1, studies that described histopathologic changes in placentas from women with known diabetes mellitus and 2) for key question 2, those that described structural-placental changes detectable by elastography in high-risk pregnancies (eg, those complicated by preeclampsia and/or fetal growth restriction), were included.

View Article and Find Full Text PDF

Introduction: The management of a patient with an ependymoma is controversial. Although the necessity for a multi-disciplined approach is accepted, the exact roles for all disciplines are poorly defined.

Review: This review article examines the current status of histopathological and cytogenetic diagnosis, surgical, chemotherapeutic and radiotherapeutic treatment and future directions.

View Article and Find Full Text PDF

Purpose: To evaluate the impact of a community-based HIV/AIDS peer leadership prevention program on newly enrolled peer leaders and youth enrolled as peer educators for one or more years (repeat peer leaders).

Methods: Quasi-experimental nonrandomized design with two intervention groups (newly enrolled and repeat peer leaders) and one comparison group. The sample consisted of 235 adolescents, 164 peer leaders, and 71 comparison youth, drawn from nine communities in Massachusetts.

View Article and Find Full Text PDF