Publications by authors named "P J Remy"
Background: Lixisenatide, a glucagon-like peptide-1 receptor agonist used for the treatment of diabetes, has shown neuroprotective properties in a mouse model of Parkinson's disease.
Methods: In this phase 2, double-blind, randomized, placebo-controlled trial, we assessed the effect of lixisenatide on the progression of motor disability in persons with Parkinson's disease. Participants in whom Parkinson's disease was diagnosed less than 3 years earlier, who were receiving a stable dose of medications to treat symptoms, and who did not have motor complications were randomly assigned in a 1:1 ratio to daily subcutaneous lixisenatide or placebo for 12 months, followed by a 2-month washout period.
Amantadine use in the French prospective NS-Park cohort.
J Neural Transm (Vienna)
July 2024
Article Synopsis
- The study aimed to evaluate the use of amantadine in patients with Parkinson's disease (PD) and its effectiveness in treating levodopa-induced dyskinesia (LIDs).
- It found that 12.6% of PD patients in the French NS-Park cohort were using amantadine, primarily younger patients with more severe symptoms and higher doses of levodopa.
- The results indicated that starting amantadine led to significant improvements in LIDs and motor fluctuations among new users compared to those who had never used the drug.
Article Synopsis
- The study investigates the characteristics of systemic lupus erythematosus (SLE) in patients also living with human immunodeficiency virus (HIV) and compares these characteristics to those in SLE patients without HIV.
- Researchers analyzed data from 13 SLE patients with HIV, noting a median diagnosis age of 43, with 77% being women, and identifying common symptoms such as joint pain and skin issues.
- The findings reveal that SLE patients with HIV exhibit more kidney problems and autoimmune blood issues compared to those without HIV, highlighting a rare but significant relationship between these conditions.
Single quantum emitters embedded in solid-state hosts are an ideal platform for realizing quantum information processors and quantum network nodes. Among the currently investigated candidates, Er^{3+} ions are particularly appealing due to their 1.5 μm optical transition in the telecom band as well as their long spin coherence times.
View Article and Find Full Text PDFOverview on wearable sensors for the management of Parkinson's disease.
NPJ Parkinsons Dis
November 2023
Parkinson's disease (PD) is affecting about 1.2 million patients in Europe with a prevalence that is expected to have an exponential increment, in the next decades. This epidemiological evolution will be challenged by the low number of neurologists able to deliver expert care for PD.
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