Publications by authors named "P J ROSENBAUM"

Addressing global health challenges requires complex coordination and collaboration between actors, often through the process of Global Health Diplomacy (GHD). Although considerable scholarship argues the importance of improving this process to build better health policies and systems, few studies have investigated the 'health diplomats' directly leading this work. In this study, we seek to better understand GHD from a practitioners' view by exploring perceptions of knowledge acquisition, capacity building, and network development amongst those who coordinate and orchestrate global policy solutions.

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Traumatic brain injury (TBI) is common and costly. Although neuroimaging modalities such as resting-state functional MRI (rsfMRI) promise to differentiate injured from healthy brains and prognosticate long-term outcomes, the field suffers from heterogeneous findings. To assess whether this heterogeneity stems from variability in the TBI populations studied or the imaging methods used, and to determine whether a consensus exists in this literature, we performed the first systematic review of studies comparing rsfMRI functional connectivity (FC) in patients with TBI to matched controls for seven canonical brain networks across injury severity, age, chronicity, population type, and various imaging methods.

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Article Synopsis
  • Researchers explored how combining DNA vaccination with a potent HBV neutralizing antibody might improve treatment for chronic HBV infections, which are hard to manage due to weak immune responses.
  • In a study with mice, treatment with the antibody and a DNA vaccine led to the development of specific immune cells in the liver, enhancing immune recruitment but also indicating T cells became dysfunctional over time.
  • While this combination therapy did not fully cure the infection, it showed promise by improving the immune response and providing insights into how the liver tolerates HBV.
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