Publications by authors named "P J McLaughlin"

Purpose: Prospective trials have reported isotoxicity and improved oncologic outcomes with external beam radiation therapy (EBRT) microboost to a dominant intraprostatic lesion. There is often variability in the rate of adoption of new treatments, and current microboost practice patterns are unknown. We leveraged prospectively collected data from the multicenter Michigan Radiation Oncology Quality Consortium to understand the current state of microboost usage for localized prostate cancer.

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Whilst some guidance exists, the literature is relatively scarce on designing and reporting on case series studies for non-surgical techniques/interventions or interventions that may be considered outside the medical model. This commentary presents a set of thirteen design attributes and an adapted checklist for consideration by clinicians when considering a case series design focused on a non-surgical intervention.

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Purpose: To determine the long-term disease-free survival, long-term toxicity, and effect on health-related quality of life of a two-fraction regimen of high-dose-rate (HDR) prostate brachytherapy.

Methods And Materials: Patients with low- or intermediate-risk prostate cancer were treated with CT-planned HDR brachytherapy as monotherapy in two implants of 13.5 Gy in one community cancer center.

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Article Synopsis
  • Chronic pain affects a significant percentage (30-71%) of individuals with haemophilia, making effective management strategies important, and this study aimed to evaluate a telerehabilitation exercise intervention for those living with chronic pain.
  • The intervention included 12 personalized low-impact exercise sessions and three discussion sessions, with a focus on participant recruitment, adherence, follow-up, fidelity, and safety.
  • Results revealed that 10 participants completed the program with a high session attendance rate (84.5%), although only minimal changes in pain and quality of life were observed, and no serious adverse events occurred.
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  • Equestrians experience higher rates of low back pain due to the physical demands of riding, prompting a targeted eight-week exercise program for those suffering from this issue.
  • Participants were recruited via social media in Melbourne, underwent screening tests, and completed pain assessments before and after the program.
  • Results showed that all nine participants experienced significant improvements in pain severity, pain interference, and riding functionality, suggesting the program effectively alleviates chronic low back pain in equestrians.
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