Publications by authors named "P J Makovicky"
Introduction: Staphylococcus aureus is a gram-positive, facultatively anaerobic coccus capable of causing infectious diseases in animals and humans. Especially dangerous are multidrug-resistant forms with poor or even no response to available treatments.
Objectives: The study aimed to verify the effect of enzybiotics on the healing of S.
Background: Bovine mastitis is one of the main causes of reduced production in dairy cows. The infection of the mammary gland is mainly caused by the bacterium Staphylococcus aureus, whose resistant strains make the treatment of mastitis with conventional antibiotics very difficult and result in high losses. Therefore, it is important to develop novel therapeutic agents to overcome the resistance of mastitis-causing strains.
View Article and Find Full Text PDFSome of the smallest examples of dinosaurian body size are from alvarezsaurians, an enigmatic group of maniraptoran coelurosaurians with a peculiar combination of anatomical features unique among theropods. Despite the large number of alvarezsaurian species described worldwide and the increased understanding this has provided, the body-size macroevolution of alvarezsaurians has received little attention. Here we reconstruct and analyse directional trends of alvarezsaurian body-size evolution through an integrated analysis of body mass, ontogenetic age, and morphological rate data enabled by a comprehensively revised phylogeny.
View Article and Find Full Text PDFPeripheral nerve sheath tumours (PNSTs) are rare in the mammary glands of dogs. Here, we report a case of a schwannoma, composed of two parts, of the mammary gland of a dog. The first part consists of clusters of uncircumscribed, alternating, more concentrated and looser regions.
View Article and Find Full Text PDFArticle Synopsis
- - The rising antibiotic resistance of Staphylococcus spp. highlights the need for effective in vivo models to evaluate new antimicrobial treatments.
- - A comprehensive porcine model was developed to simulate extensive skin and soft tissue damage, facilitating the testing of topical antimicrobial agents through a multi-stage protocol.
- - The model demonstrated persistent infection with Staphylococcus aureus throughout the study, confirming its effectiveness for testing short-acting topical antibiotics.