Publications by authors named "P J Lang"
Background And Purpose: We investigate discrepancies in the assessment of treatment-related symptoms in lung cancer between healthcare professionals and patients, and factors contributing to these discrepancies.
Materials And Methods: Data from 515 participants in the REQUITE study were analysed. Five symptoms (cough, dyspnoea, bronchopulmonary haemorrhage, chest wall pain, dysphagia) were evaluated both before and after radiotherapy.
Pharmaceutical and biotechnology companies are increasingly being challenged to shorten the cycle time between design, make, test, and analyze (DMTA) compounds. Automation of multiplex assays to obtain multiparameter data on the same robotic run is instrumental in reducing cycle time. Consequently, an increasing need in automated systems to streamline laboratory workflows with the goal to expedite assay cycle time and enhance productivity has grown in industrial and academic institutions in the past decades.
View Article and Find Full Text PDFArticle Synopsis
- * An analysis of 1,192 participants revealed elevated sACE2 activity following exposure to SARS-CoV-2, especially in children, indicating a significant response regardless of infection status.
- * The research suggests that increased sACE2 activity could help manage SARS-CoV-2 infections, proposing a more nuanced understanding of immune responses beyond traditional infection classifications.
Article Synopsis
- Immune function declines with age, making it difficult to identify individuals at risk for immune-related issues, especially those with reactivated latent viral infections.
- The study focused on detecting certain human herpes viruses in urine as a potential way to identify immune-compromised individuals, particularly using T cell receptor excision circle (TREC) data as an indicator.
- While no clear one-to-one correlation was found between TREC values and individual viruses, a significant link was observed for males; specifically, low TREC values correlated with the detection of three or more different herpes viruses, suggesting declining immune function.
Background/objectives: This study examines job satisfaction, burnout, and well-being among first-generation migrant physicians in anesthesiology and intensive care medicine in Germany, comparing them to their native German counterparts.
Methods: A cross-sectional survey design was utilized, collecting data from 513 physicians, 110 of whom identified as having a migration background. Job satisfaction was measured using the Warr-Cook-Wall (WCW) Job Satisfaction Scale, burnout was assessed with the Copenhagen Burnout Inventory (CBI), and well-being was evaluated using the WHO-5 Well-Being Index.