Single Nucleotide Polymorphism in the 3' Untranslated Region of on Cardiometabolic Parameters in Type 2 Diabetes Mellitus Patients Who Received Metformin.

Purpose: This study aimed to explore the association of A>C as 3'UTR variants with blood pressure, HbA1c profile, and lipid profiles as cardiometabolic parameters among patients with T2DM receiving metformin.

Patients And Methods: This cross-sectional analytic research was conducted with 114 consecutively selected patients with T2DM. Polymerase chain reaction-restriction fragment length polymorphism was conducted to determine .

Synthesis of benzophenone glucopyranosides from Phaleria macrocarpa and related benzophenone glucopyranosides.

The first total syntheses of benzophenone glucopyranosides reported from Phaleria macrocarpa and related benzophenone glucopyranosides were successfully carried out. The alkoxy groups present ortho to the carbonyl group in polyalkoxybenzophenones were selectively deprotected by AlCl(3)-PhNMe(2) in high yields, leaving other alkoxy groups unaffected. It was concluded in the current synthetic study that all the reported benzophenone glucopyranosides possessed the same structure as 2,4',6-trihydroxy-4-methoxybenzophenone 2-O-beta-D-glucopyranoside.

The use of reference materials in quantitative analyses based on FT-Raman spectroscopy.

The reliability with which an external reference sample can be used to standardise the intensities of Raman scattering spectra is assessed. By comparing the ratios of single band intensities of Raman scatter in a two component liquid mixture with those between the mixture and an external standard it is shown that the latter is more than adequate for most quantitative Raman analysis. Coefficients of variance in repeated experiments on the same sample are approximately 1%, when comparing single band heights on spectra recorded with modest laser powers over 2 min.

Rotating samples in FT-RAMAN spectrometers.

It is customary to rotate samples in Raman spectroscopy to avoid absorption or sample heating. In FT-Raman experiments the rotation is always shown (typically 30-60 rpm) because higher speeds are thought to generate noise in the spectra. In this article we show that more rapid rotation is possible.