Am J Health Syst Pharm
March 2015
Purpose: Study results demonstrating the effectiveness of order-entry clinical decision support (CDS) alerts as a tool for enforcing therapeutic interchange are presented.
Methods: A retrospective observational study was conducted at an academic medical center to evaluate formulary nonadherence before and after implementation of a fully electronic medical record with computerized prescriber order-entry (CPOE) technology configured to display therapeutic interchange alerts immediately on entry of orders for nonformulary agents. Formulary nonadherence (defined as the proportion of pharmacist-verified nonformulary orders to total verified orders) within eight medication classes was assessed during a six-month baseline period and two consecutive six-month periods after implementation.
Background: Drug-drug interactions (DDIs) are very prevalent in hospitalized patients.
Objectives: To determine the number of DDI alerts, time saved, and time invested after suppressing clinically irrelevant alerts and adding clinical-decision support to relevant alerts.
Materials And Methods: The most frequently occurring DDIs were evaluated for clinical relevance by a multidisciplinary expert panel.
Purpose: The impact of a comprehensive hospital formulary management system on formulary compliance and pharmacy labor costs was evaluated.
Methods: The formulary management system consisted of monitoring nonformulary medication use, reviewing formulary medication use annually, and providing periodic feedback. Workflow scenarios for nonformulary medication requests were identified.
Biol Blood Marrow Transplant
September 2013
Adequate hematopoietic stem cell (HSC) mobilization and collection is required prior to proceeding with high dose chemotherapy and autologous hematopoietic stem cell transplant. Cytokines such as G-CSF, GM-CSF, and peg-filgrastim, alone or in combination with plerixafor, and after chemotherapy have been used to mobilize HSCs. Studies have shown that the efficiency of HSC mobilization and collection may vary when different methods of mobilization are used.
View Article and Find Full Text PDFAm J Health Syst Pharm
October 2012
Purpose: The effects of a direct refill program for automated dispensing cabinets (ADCs) on medication-refill errors were studied.
Methods: This study was conducted in designated acute care areas of a 386-bed academic medical center. A wholesaler-to-ADC direct refill program, consisting of prepackaged delivery of medications and bar-code-assisted ADC refilling, was implemented in the inpatient pharmacy of the medical center in September 2009.