Publications by authors named "P J Hastings"

Nutrition and the home environment contribute to the development of the autonomic nervous system (ANS). However, no study has examined the long-term effects of prenatal and postnatal small-quantity lipid-based nutrient supplements (SQ-LNS) and home environment on ANS regulation. We investigated the effect of early-life SQ-LNS and home environment on ANS regulation at 9-11 years.

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Formation of templated insertions at DNA double-strand breaks (DSBs) is very common in cancer cells. The mechanisms and enzymes regulating these events are largely unknown. Here, we investigated templated insertions in yeast at DSBs using amplicon sequencing across a repaired locus.

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Article Synopsis
  • Warm and supportive parenting is linked to better emotion regulation in children, but less is understood about its impact on adolescents, especially during a time when mental health issues often emerge.
  • The study focused on how maternal and paternal warmth from ages 10 to 16 affects adolescents' respiratory sinus arrhythmia (RSA), a measure related to emotion regulation, at age 17 in a sample of 229 Mexican-origin youths.
  • Results indicated that increases in maternal warmth during adolescence were connected to higher RSA in youths, suggesting that positive maternal interactions can enhance emotional regulation capabilities in teens.
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  • Childhood adversity (CA) is linked to higher risks of negative health outcomes, with differences in how various types of adversity affect brain structure during development.
  • Recent research indicates that deprivation leads to slower decreases in cortical surface area in certain brain regions, while threat exposure results in increased surface area in areas related to socio-emotional processing as adolescents age.
  • These findings suggest a need to reconsider how different forms of adversity affect brain development over time, highlighting the varying impacts on cognitive and emotional functions.
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