Publications by authors named "P J Hanly"
Article Synopsis
- Obstructive sleep apnea (OSA) has been linked to an increased risk of cognitive impairment, and EEG sleep microarchitecture measures could help identify at-risk individuals.
- A study with 1,142 suspected OSA patients assessed various cognitive functions and analyzed associations between cognitive scores and specific EEG characteristics during sleep, finding that spindle density and normalized EEG power were significantly lower in those with moderate to severe OSA.
- The research concluded that changes in spindle activity and EEG measures might play a critical role in understanding cognitive deficits experienced by OSA patients.
Obstructive sleep apnea (OSA) severity is typically assessed by the apnea-hypopnea index (AHI), a frequency-based metric that allocates equal weight to all respiratory events. However, more severe events may have a greater physiologic impact. The purpose of this study was to determine whether the degree of event-related hypoxemia would be associated with the postevent physiologic response.
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- Recent research shows a potential connection between obstructive sleep apnea and cognitive decline, but the exact reasons behind this link are not fully understood.
- The study involved 125 middle-aged and older adults, evaluating their sleep patterns and cognitive function, which included analyzing sleep spindles during specific sleep stages using polysomnography.
- Findings indicated that the characteristics of sleep spindles were more closely related to certain verbal fluency scores rather than severity of obstructive sleep apnea, suggesting that biological sex may also influence these relationships.
Background: About half of cancer deaths in Brazil occur among individuals of working-age (under 65 years for men, under 60 for women), resulting in a substantial economic impact for the country. We aimed to estimate the years of potential productive life lost (YPPLL) and value the productivity lost due to premature deaths from cancer between 2001 and 2015 and the projected to 2030.
Methods: We used the Human Capital Approach to estimate the productivity losses corresponding to YPPLL for cancer deaths in working age people (15-64 years).