Publications by authors named "P J Gardiner"

Importance: During buprenorphine treatment for opioid use disorder (OUD), risk factors for opioid relapse or treatment dropout include comorbid substance use disorder, anxiety, or residual opioid craving. There is a need for a well-powered trial to evaluate virtually delivered groups, including both mindfulness and evidence-based approaches, to address these comorbidities during buprenorphine treatment.

Objective: To compare the effects of the Mindful Recovery Opioid Use Disorder Care Continuum (M-ROCC) vs active control among adults receiving buprenorphine for OUD.

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Background: The well-being of healthcare teams is an important consideration when seeking to improve patient experience and quality of care. Prior studies have found that changes to working conditions are most effective in improving clinician well-being. Integrative Group Medical Visits (IGMVs) modify working conditions in ways that have potential to improve clinician experience.

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The lived experiences of psychiatric inpatients are not well represented in the literature, especially when these experiences pertain to health. Reports regarding sleep health are particularly sparse, despite the increasing prevalence of sleep disorders in this population. The current study aimed to explore inpatient and staff perspectives of inpatient sleep quality to aid the future development of a sleep quality intervention.

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Article Synopsis
  • Cellular senescence refers to the permanent halt of cell growth caused by factors like genetic mutations or damage, and it's linked to aging and diseases like diabetes and heart issues.
  • The study aimed to identify specific senescence biomarkers in patients with acute kidney injury (AKI) and chronic kidney disease (CKD) using OLINK proteomics.
  • The proteins CKAP4 and PTX3 were found to be significantly elevated in AKI and CKD patients, suggesting they could serve as important indicators for kidney disease progression.
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Background: Menopause represents a pivotal physiological transition characterized by hormonal fluctuations and an augmented susceptibility to chronic diseases. The relationship between menopause and heightened disease risk may be attributed in part to alterations in low-grade chronic inflammation and adiposity.

Methods: Three databases were searched for studies assessing differences in inflammation and body adiposity between pre- and postmenopausal women.

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