Publications by authors named "P J Escourrou"

Snoring may be a risk factor for cardiovascular disease independent of other co-morbidities. However, most prior studies have relied on subjective, self-report, snoring evaluation. This study assessed snoring prevalence objectively over multiple months using in-home monitoring technology, and its association with hypertension prevalence.

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Objectives: Evidence-based guidelines recommend that adults should sleep 7-9 h/night for optimal health and function. This study used noninvasive, multinight, objective sleep monitoring to determine average sleep duration and sleep duration variability in a large global community sample, and how often participants met the recommended sleep duration range.

Methods: Data were analyzed from registered users of the Withings under-mattress Sleep Analyzer (predominantly located in Europe and North America) who had ≥28 nights of sleep recordings, averaging ≥4 per week.

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Obstructive sleep apnea (OSA) severity can vary markedly from night-to-night. However, the impact of night-to-night variability in OSA severity on key cardiovascular outcomes such as hypertension is unknown. Thus, the primary aim of this study is to determine the effects of night-to-night variability in OSA severity on hypertension likelihood.

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Article Synopsis
  • Irregular sleep patterns, including changes in sleep duration and timing, may increase the risk of hypertension, as indicated by a study involving over 12,000 adults.
  • The study found that disruptions in sleep duration were linked to a 9% to 17% increase in hypertension risk, while specific timing irregularities like late sleep onset resulted in a 32% increase in hypertension.
  • These results suggest that both sleep irregularity in duration and timing are important factors for cardiovascular health, warranting further research on their effects on blood pressure and heart health.
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Background: Single-night disease misclassification of OSA due to night-to-night variability may contribute to inconsistent findings in OSA trials.

Research Question: Does multinight quantification of OSA severity provide more precise estimates of associations with incident hypertension?

Study Design And Methods: A total of 3,831 participants without hypertension at baseline were included in simulation analyses. Included participants had ≥ 28 days of nightly apnea-hypopnea index (AHI) recordings via an under-mattress sensor and ≥ three separate BP measurements over a 3-month baseline period followed by ≥ three separate BP measurements 6 to 9 months postbaseline.

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